Hospital doctor until March 2019 at Hôpital Bichat (AP-HP, Paris). Originally a cardiologist, he has been a specialist in internal medicine since 1998.​​

He has been an associate professor at Paris Descartes University since 1992, and was appointed Director of Teaching at Paris Saclay University in 2002. His teaching and research activities focus on health policy and economics. He is also Associate Professor at the Université Pierre et Marie Curie / Sorbonne Universités.​​

He is considered to be an expert on the introduction of innovation in the healthcare sector, whether in terms of healthcare products, drugs, medical devices or the organisation of care: healthcare financing, care pathways, digital health, etc.​​

He advises French and European government bodies as well as various institutional players and companies in the healthcare sector, manufacturers (LEEM, SNITEM, etc.) and professional bodies (medical and pharmaceutical associations and unions). ​​

He is also a consultant to French and foreign financial institutions on issues relating to the economics of healthcare and healthcare-related industries and services.He is the author of numerous books, publications and papers on health policy and economics, particularly on financing and access to innovation.​​

Highly involved in the digital health sector, he is also General Delegate of the Société Française de Télémédecine. He is also a member of the Société Française de Cardiologie, the Société Française de Médecine Interne, the Société Française de Médecine Aéronautique et Spatiale, the Société Française et Francophone d’Ethique Médicale, the International Society for Pharmacoeconomics and Outcomes Research and the Health Technology Assessment International Conference.​​

He is also an Officer of the Légion d’Honneur (2020) and a Knight of the Ordre National du Mérite (1991).​